Peter Neumark has made Fast CGI work by following the instructions for Using CGI with the following index.fcgi:

import os
import sys
from flup.server.fcgi import WSGIServer
from wsgiref.handlers import BaseCGIHandler
from tiddlyweb.web import serve

tiddlywebconfig_dir = '...'
os.chdir(tiddlywebconfig_dir)
sys.path.insert(0, tiddlywebconfig_dir)


def start():
    app = serve.load_app(app_prefix='')
    WSGIServer(app).run()

if __name__ == '__main__':
    start()


His announcement.