WSGI is "Web Server Gateway Interface"

The WSGI Wiki says:

"It is a specification for web servers and application servers to communicate with web applications (though it can also be used for more than that). It is a Python standard, described in detail in PEP 333."

WSGI is useful to TiddlyWeb for three reasons:
A WSGI application is identified by the signature of a function or class and the contract of its return value. A WSGI application is a callable that takes environ and start_response as arguments, returning an iterator.